Exposure To Chemicals Related To Autism In Children

November 3, 2021

A new study by researchers from the Simon Fraser University School of Health Sciences has found correlations between increased expressions of autistic-like behaviors in preschool-age children and exposure during pregnancy to certain environmental toxins, such as metals, pesticides, polychlorinated biphenyls (PCBs), phthalates, and bisphenol-A (BPA).

This population-based study measured the levels of 25 chemicals in blood and urine samples collected from 1,861 Canadian women during the first trimester of pregnancy. A follow-up survey was conducted with 478 participants, using the Social Responsiveness Scale (SRS) tool to assess autistic-type behaviors in preschool children.

Researchers found that higher maternal concentrations of cadmium, lead, and some phthalates in blood or urine samples were associated with increased SRS scores, and these associations were especially strong among children with a higher degree of type behaviors. autistic. Interestingly, the study also found that increased maternal concentrations of manganese, trans-nonachlor, many organophosphate pesticide metabolites, and monoethyl phthalate (MEP) were more strongly associated with lower SRS scores.

Study lead author Josh Alampi notes that this study primarily “highlights the relationships between certain environmental toxins and increased SRS scores. More studies are needed to fully assess the links and impacts of these environmental chemicals on brain development during pregnancy. ”

The results were obtained using a statistical analysis tool, called Bayesian quantitative regression, which allowed the researchers to determine which individual toxins were associated with increased SRS scores in a more nuanced way than conventional methods.

“The relationships we found between these toxicants and the SRS scores would not have been detected using a means-based statistical analysis method (such as linear regression),” Alampi noted. “Although quantile regression is not often used by researchers, it can be a powerful way to analyze complex population-based data.”

Dr. Loony Davis5
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Born and raised in Brussels in an English family, I have always lived in a multicultural environment. After several work experiences in marketing and communication, I came to Smart Water Magazine, which I describe as the most exciting challenge of my career.
I am a person with great restlessness and curiosity to learn, discover what I do not know, as well as reinvent myself daily, someone who is curious about life and wants to know. I enjoy sharing knowledge.
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